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KMID : 0614620080510050305
Korean Journal of Gastroenterology
2008 Volume.51 No. 5 p.305 ~ p.308
Spontaneous Resolution of Multiple Fundic Gland Polyps after Cessation of Treatment with Omeprazole
Kim Jin-Soo

Chae Hiun-Suk
Kim Hyung-Keun
Cho Young-Seok
Park Yong-Wan
Son Hye-Suk
Han Sok-Won
Choi Gyu-Yong
Abstract
Fundic gland polyps (FGPs) are the most common type of gastric polyps, found primarily in the fundus and body of stomach. Long term use of proton pump inhibitor (PPI) is known to be associated with certain histological changes of the normal gastric mucosa including parietal cell hyperplasia and fundic gland cysts. We experienced a patient who showed spontaneous resolution of multiple FGPs after the cessation of omeprazole. Two years ago, the patient showed only endoscopically confirmed erosive esophagitis without FGPs. Multiple FGPs developed one year after the use of omeprazole and spontaneously disappeared with the cessation of omeprazole.
KEYWORD
Fundic gland polyp, Proton pump inhibitor, Microcyst
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